**英国剑桥大学研究人员利用AI技术加速帕金森病药物研发**
英国剑桥大学的科研团队近日取得一项重大突破，他们成功地利用人工智能（AI）技术将帕金森病药物的设计过程提升了十倍效率。这一创新方法有望极大地加快帕金森病治疗方法的开发速度，为全球数百万帕金森病患者带来新的希望。
据科技日报报道，研究人员针对帕金森病的特征蛋白——α-突触核蛋白，设计了一种基于AI的智能策略。该策略能够高效地识别出能够阻止这种蛋白聚集的小分子，而蛋白聚集正是帕金森病发病的关键因素。通过AI技术，研究团队不仅显著提高了药物筛选的效率，还将成本降低了千分之一，极大地降低了研发成本。
这一突破性的研究成果已发表在最新一期的《自然·化学生物学》杂志上。研究人员表示，这一进展意味着潜在帕金森病疗法的研发速度将显著加快，为临床试验和最终的患者应用铺平了道路。这一创新应用展示了AI在生物医学研究中的巨大潜力，预示着未来药物研发领域可能发生的革命性变革。
英语如下：
**News Title:** “Cambridge University AI Boost: Drug Development for Parkinson’s Disease Accelerated Tenfold”
Keywords: AI制药, 帕金森病, 研究突破
**News Content:**
**Cambridge University Researchers Harness AI to Speed Up Parkinson’s Disease Drug Discovery**
A major breakthrough has been achieved by a research team from the University of Cambridge, as they successfully运用人工智能 (AI) technology to boost the efficiency of Parkinson’s disease drug development by a factor of ten. This innovative approach promises to significantly accelerate the development of treatments for Parkinson’s, offering new hope to millions of patients worldwide.
According to a report in the Science and Technology Daily, the researchers targeted the characteristic protein of Parkinson’s disease, α-synuclein. They developed an AI-driven intelligent strategy that efficiently identifies small molecules capable of preventing the aggregation of this protein, a key factor in the onset of Parkinson’s. By employing AI technology, the team not only enhanced the efficiency of drug screening but also reduced costs by one thousandth, substantially lowering the R&D expenses.
This groundbreaking research has been published in the latest issue of *Nature Chemical Biology*. Researchers claim that this progress signals a significant acceleration in the development of potential Parkinson’s therapies, paving the way for clinical trials and eventual application in patients. This pioneering application showcases the tremendous potential of AI in biomedical research and foreshadows a potentially revolutionary shift in the future of drug development.
【来源】http://digitalpaper.stdaily.com/http_www.kjrb.com/kjrb/html/2024-04/22/content_570458.htm?div=-1
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