中新网3月22日电 据美国有线电视新闻网(CNN)报道，当地时间21日，美国马萨诸塞州总医院表示，该医院成功操作了世界首例将基因编辑猪的肾脏移植到活体人类受体中的手术。这标志着医学界在解决器官短缺问题上的一个重大突破。
手术中，医生将一个经过基因编辑的猪肾，通过外科手术成功植入了一名肾功能衰竭、且不适合接受传统肾脏移植的患者体内。这个猪肾在移植后立即开始工作，为患者提供了肾功能，并且没有立即引起排异反应。
此次手术的成功，得益于基因编辑技术的进步。研究人员通过CRISPR-Cas9等技术，对猪的基因进行了修改，去除了可能引起人类免疫系统排斥的基因，并增加了人类所需的关键基因。
马萨诸塞州总医院的团队表示，这只是一个开始，他们将继续监测患者的情况，并希望在未来能够将这一技术推广到更多的患者身上。此外，他们还将进一步研究如何提高猪器官在人体内的长期存活率，以及如何解决可能出现的其他医学挑战。
这项手术的成功，不仅为数百万等待器官移植的患者带来了希望，也为未来解决器官短缺问题提供了新的可能性。随着技术的不断发展和完善，猪器官移植有望成为一种常规的治疗手段，为更多的患者带来新生。
英文标题：First-ever transplant of a genetically modified pig kidney into a human
英文关键词：Genetically modified, pig kidney, medical breakthrough
英文新闻内容：
CNN, March 21 – Massachusetts General Hospital in the United States has announced the successful completion of the world’s first surgery to transplant a genetically modified pig kidney into a living human recipient. This marks a significant breakthrough in addressing the issue of organ shortages.
During the surgery, doctors implanted a kidney from a pig that had been genetically modified using CRISPR-Cas9 technology to remove genes that could trigger human immune system rejection and to add key human genes. The modified kidney immediately began functioning for the patient, who suffered from kidney failure and was not a suitable candidate for traditional kidney transplants.
The team at Massachusetts General Hospital emphasized that this is just the beginning and that they will continue to monitor the patient’s condition. They hope to expand this technique to more patients in the future and to further research how to enhance the long-term survival rate of pig organs in humans and to address other potential medical challenges.
The success of this surgery not only offers hope to the millions of patients等待ing organ transplants but also provides a new possibility for solving the problem of organ shortages. As technology continues to advance and improve, pig organ transplants have the potential to become a standard treatment option, offering new life to many more patients.
【来源】http://www.chinanews.com/gj/2024/03-22/10184908.shtml
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