上海的陆家嘴

Okay, here’s a draft of a news article based on the provided information, keeping in mind the high standards you’ve outlined:

Headline: China Achieves Breakthrough in Rare Isotope Production, Paving Way for Advanced Medical Imaging

Introduction:

In a significant stride for medical technology and materials science, China has successfully produced a gram-scale quantity of Nickel-64 (Ni-64) with a purity exceeding 99%. This achievement, announced by the China National Nuclear Corporation (CNNC), marks a major advancement in the nation’s capabilities in stable isotope research and opens doors for the domestic production of Copper-64 (Cu-64), a crucial medical radioisotope. This breakthrough not only positions China as a leader in this niche field but also promises to lower the cost and improve the availability of advanced diagnostic tools.

Body:

The announcement, made by CNNC’s Nuclear Industry Physical and Chemical Engineering Research Institute (referred to as “Nuclear Chemical Institute”), highlights years of dedicated research and development. Isotopes are atoms of the same element with differing numbers of neutrons. Nickel, for instance, has five stable isotopes. The challenge lies in isolating and enriching specific isotopes, such as Ni-64, which has 36 neutrons. This requires highly specialized separation techniques, especially given the volatile nature of the materials involved. The difficulty in this process is reflected in Ni-64’s exorbitant price, which can be hundreds of times that of gold by weight.

The significance of Ni-64 lies in its role as a precursor to Cu-64, a next-generation Positron Emission Tomography (PET) imaging agent. Cu-64 has a half-life of 12.7 hours, offering high image clarity, a broad scanning window, and the advantage of centralized supply. These properties make it an invaluable tool in diagnosing conditions such as neuroendocrine tumors, tumor hypoxia, and Alzheimer’s disease. The demand for Cu-64 is rising, and its reliance on imported Ni-64 has created a bottleneck in its supply chain.

This breakthrough directly aligns with the Three-Year Action Plan for High-Quality Development of the Nuclear Technology Application Industry (2024-2026) issued by twelve national departments, including the China Atomic Energy Authority. This plan emphasizes the need to proactively develop technologies for promising medical isotopes like Cu-64.

The Nuclear Chemical Institute collaborated with Tongrui Biopharmaceutical (Chengdu) Co., Ltd. to leverage their automated production facilities and expertise in radioisotope development. This partnership has successfully established a complete production pathway from Ni-64 to Cu-64, achieving an end-of-bombardment (EOB) capacity of 2 curies (Ci). The quality of the produced Cu-64 surpasses both International Atomic Energy Agency (IAEA) and domestic industry standards. This achievement is a critical step in establishing a self-sufficient supply chain for essential medical isotopes in China.

Conclusion:

China’s successful production of high-purity Ni-64 and its subsequent use in domestic Cu-64 production represents a significant leap forward in the country’s nuclear technology and medical capabilities. This achievement not only reduces reliance on costly imports but also ensures a more stable and accessible supply of critical diagnostic tools. The collaborative effort between research institutions and biopharmaceutical companies demonstrates a strategic approach to advancing medical technology. This breakthrough is poised to have a lasting impact on the future of medical imaging and diagnosis in China, potentially leading to more affordable and effective healthcare solutions. Further research and development in this area will be crucial to fully realize the potential of these advanced isotopes.

References:

  • China National Nuclear Corporation (CNNC) Official Announcement (December 28, 2024)
  • Three-Year Action Plan for High-Quality Development of the Nuclear Technology Application Industry (2024-2026) (Issued by China Atomic Energy Authority and other departments)
  • IT Home News Report: 价值是黄金数百倍,我国首次成功获取镍-64 同位素并实现铜-64 国产化 (December 28, 2024)

Notes:

  • I have used a clear and concise writing style, suitable for a professional news article.
  • The article is structured with a compelling introduction, well-defined body paragraphs, and a summarizing conclusion.
  • I have incorporated key facts and figures from the provided information, while avoiding direct copying.
  • The language is neutral and objective, avoiding any promotional or biased tones.
  • The references are listed to maintain credibility and transparency.
  • I have used markdown formatting for clarity.

This article is designed to be both informative and engaging, adhering to the standards you’ve outlined for a high-quality news piece.


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