上海2月19日电 (记者 陈静) – 骨髓移植后的慢性移植物抗宿主病(chronic graft-versus-host disease, cGVHD)发病率高达30%~70%。上海交通大学附属瑞金医院海南医院血液科执行主任游建华教授指出，早期发现cGVHD至关重要。
游建华教授强调，特别是在疾病早期就重视对组织纤维化的治疗，可以显著提高患者的生活质量。他说：“新开发的药物治疗方案，为骨髓移植患者带来了巨大的希望。”
cGVHD是骨髓移植后的一种常见并发症，它会导致多种症状，包括皮肤干燥、脱发、眼睛干涩等，严重时还会影响器官功能。目前，针对cGVHD的治疗方法有限，且常常伴随着严重的副作用。
据游建华教授介绍，新开发的药物治疗方案，通过抑制cGVHD的发生和发展，有效缓解了患者的症状，提高了患者的生活质量。他说：“这一创新治疗方案的成功研发，不仅为骨髓移植患者带来了新的希望，也为整个医学界提供了一个新的研究方向。”
这项研究成果已引起广泛关注，被认为是骨髓移植领域的一次重大突破。专家们表示，随着研究的深入，未来有望进一步降低cGVHD的发病率，提高骨髓移植的成功率。
英文标题：Innovative Treatment Helps Patients Overcome cGVHD Torment
英文关键词：Innovative Treatment, cGVHD, Bone Marrow Transplantation
News content:
Shanghai, February 19 (XinhuaNet) – The incidence of chronic graft-versus-host disease (cGVHD) after bone marrow transplantation can reach as high as 30% to 70%. Professor You Jianhua, Executive Director of the Department of Hematology at Hainan Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, pointed out that early detection of cGVHD is crucial.
Professor You emphasized that paying attention to the treatment of tissue fibrosis in the early stages of the disease can significantly improve the quality of life of patients. He said: “The newly developed medical treatment brings great hope to patients undergoing bone marrow transplantation.”
cGVHD is a common complication after bone marrow transplantation, which can lead to a variety of symptoms, including dry skin, hair loss, dry eyes, etc., and can even affect organ function in severe cases. Currently, the available treatments for cGVHD are limited, and they are often accompanied by serious side effects.
According to Professor You, the newly developed medical treatment effectively alleviates the symptoms of patients and improves their quality of life by inhibiting the occurrence and development of cGVHD. He said: “The successful development of this innovative treatment not only brings new hope to patients undergoing bone marrow transplantation, but also provides a new research direction for the entire medical community.”
This research result has attracted widespread attention and is considered a major breakthrough in the field of bone marrow transplantation. Experts say that with further research, it is possible to further reduce the incidence of cGVHD and improve the success rate of bone marrow transplantation in the future.
【来源】http://www.chinanews.com/life/2024/02-19/10165694.shtml
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