【深圳,4月24日】中国科学院深圳先进技术研究院和新型研究型大学——深圳理工大学(筹)生命健康学院的助理教授周航领导的研究团队近日取得重大科研突破,他们与国内外合作伙伴共同揭示了大脑海马区神经元突触群体的组织原则,这一发现可能为抗衰老药物及其他神经疾病治疗的研发开辟新路径。

据深圳理工大学(筹)官方消息,周航团队在长时间的实验研究中,对大脑海马区神经元树突分枝上的突触群体进行了深入探索,首次明确了这一关键区域神经元之间的连接模式和功能机制。海马区在记忆和学习过程中起着至关重要的作用,而突触是神经元间信息传递的关键结构。

研究发现,神经元树突上的突触并非随机分布,而是遵循特定的组织原则,这种有序的结构对于神经信号的处理和存储至关重要。这一发现对于理解大脑信息处理的精细机制提供了新的视角,也为针对神经退行性疾病,如阿尔茨海默病、帕金森病等,以及与衰老相关的认知功能衰退的药物研发提供了理论基础。

周航表示,这一研究成果有望推动神经科学领域的深入研究,并可能为未来开发更精准、更有效的治疗策略打开大门。目前,研究团队正与相关领域的专家合作,探讨如何将这些新发现转化为临床应用,以期为人类健康带来实质性的改善。

这一科研成果的发布,再次彰显了中国在生命科学领域的前沿探索和创新能力,也体现了深圳理工大学(筹)在科研教育方面取得的显著进步。

英语如下:

**News Title:** “Chinese Research Team Discovers New Principles in Neural Synapse Clusters, Paving the Way for Anti-Aging Drug Development”

**Keywords:** Neural Synapses, Group Organization, Anti-Aging Research

**News Content:**

**Shenzhen, April 24** – A research team led by Assistant Professor Zhou Hang, from the Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, and the School of Life and Health Sciences at the yet-to-be-established Shenzhen University of Technology, has recently made a significant scientific breakthrough. Collaborating with domestic and international partners, they have uncovered the organizational principles of neural synapse clusters in the hippocampus, a finding that could open new avenues for the development of anti-aging medications and treatments for neurological diseases.

According to official sources from Shenzhen University of Technology (in preparation), Zhou Hang’s team, after extensive experimental research, delved into the synaptic clusters on the dendritic branches of neurons in the hippocampus, elucidating for the first time the connection patterns and functional mechanisms in this critical brain region. The hippocampus plays a vital role in memory and learning, and synapses are the key structures facilitating information transfer between neurons.

The study revealed that synapses on neuronal dendrites are not distributed randomly but follow specific organizational principles, a structured arrangement crucial for neural signal processing and storage. This new insight offers a fresh perspective on understanding the fine mechanisms of brain information processing and lays a theoretical foundation for drug development targeting neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, as well as age-related cognitive decline.

Zhou Hang remarked that this research outcome could propel further studies in neuroscience and potentially open doors to the development of more precise and efficacious therapeutic strategies. Currently, the research team is collaborating with experts in related fields to explore how these findings can be translated into clinical applications, aiming to bring substantial improvements to human health.

This scientific achievement underscores China’s forefront exploration and innovation in the life sciences and highlights the notable advancements made by Shenzhen University of Technology (in preparation) in research and education.

【来源】http://www.chinanews.com/sh/2024/04-24/10205404.shtml

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