**初创公司Profluent开创历史，AI设计的基因编辑器成功编辑人类DNA**
北京——创新科技领域迎来重大突破，初创公司Profluent近日宣布，其研发的首个完全由人工智能设计的基因编辑器已经成功实现了对人类细胞DNA的精准编辑。这一里程碑式的成就标志着AI技术在生物科学领域的应用迈出了革命性的一步。
Profluent的这款AI系统，类比于ChatGPT的文本生成能力，能够为基因编辑生成分子级别的精确蓝图。通过深度学习和大规模数据集，研究团队在广泛的基于CRISPR的基因编辑系统基础上训练了大型语言模型（LLM）。据新智元报道，这些经过训练的LLM极大地扩展了CRISPR-Cas家族的蛋白质多样性，将其范围扩大了4.8倍。
这一创新意味着，科学家们现在拥有了一个工具，能够以前所未有的精度和范围对DNA进行操作。这项技术的潜力在于，它有可能开启个性化医疗的新篇章，例如定制化治疗遗传疾病，甚至可能影响未来人类的进化。
尽管这一进展带来了巨大的科学兴奋和期待，但同时也引发了关于伦理和安全性的讨论。Profluent公司及其科研团队将如何平衡科技进步与潜在风险，确保技术的负责任使用，将成为未来关注的焦点。
Profluent的这一成就再次证明，人工智能不仅在改变我们的日常生活，还在探索生命科学的最前沿发挥着关键作用。随着技术的不断成熟，我们有理由期待更多基于AI的创新将重塑生物医学的未来。
英语如下：
**”Profluent Breaks Ground: AI-Designed Gene Editor Accurately Edits Human DNA”**
Keywords: AI gene editor, Profluent company, CRISPR technology
**Startup Profluent Makes History with AI-Designed Gene Editor for Precise Human DNA Editing**
Beijing — A major breakthrough in innovative technology has been announced as startup Profluent reveals that its AI-developed gene editor has successfully executed precise editing of human DNA. This milestone achievement signifies a revolutionary step in the application of AI within the biosciences.
Profluent’s AI system, akin to ChatGPT’s text generation capabilities, generates molecularly precise blueprints for gene editing. By leveraging deep learning and vast datasets, the research team trained large language models (LLMs) on a broad range of CRISPR-based gene editing systems. According to New Wisdom Monthly, these trained LLMs have expanded the protein diversity of the CRISPR-Cas family by 4.8 times.
This innovation empowers scientists with a tool to manipulate DNA with unprecedented precision and scope. The technology’s potential lies in its ability to usher in a new era of personalized medicine, potentially enabling customized treatments for genetic diseases and even influencing future human evolution.
While this advancement elicits tremendous scientific excitement and anticipation, it also sparks discussions on ethics and safety. How Profluent and its research team will balance technological progress with potential risks and ensure responsible use will be a key focus moving forward.
Profluent’s accomplishment underscores that AI is not only transforming our daily lives but also playing a pivotal role at the forefront of life sciences. As the technology continues to mature, we can reasonably anticipate more AI-driven innovations reshaping the future of biomedicine.
【来源】https://mp.weixin.qq.com/s/A3qZHVa0-MxQnkGzsm9KrA
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