红斑狼疮等自身免疫性疾病为何在女性中更为常见？科技日报记者张梦然报道，最新研究发现，女性一半的X染色体上发现的分子涂层可能引发不必要的免疫反应，为这一现象提供新答案。研究结果发表在最新一期的《细胞》杂志上。
长期以来，科学家们一直试图揭示红斑狼疮等疾病性别差异的成因。此次研究发现，女性X染色体上的分子涂层可能是关键因素。分子涂层通常在女性一半的X染色体上，而男性只有一个X染色体，因此涂层在女性体内可能引发更强烈的免疫反应。
这项研究的发现有助于进一步提高对红斑狼疮等疾病性别差异的认识，为未来针对性的治疗和预防提供理论依据。研究人员表示，未来将继续探索分子涂层如何影响免疫系统，以期为患者提供更有效的治疗手段。
Title: Why women are more susceptible to lupus than men
Keywords: lupus, women, X chromosome
News content:
Why do women have a higher incidence of autoimmune diseases such as lupus? A new study provides an explanation: the molecular coating usually found on half of the X chromosomes in women may cause unnecessary immune reactions. The research was published in the latest issue of the journal “Cell”.
Long has been the quest to uncover the cause of gender differences in diseases such as lupus. This latest discovery finds that the molecular coating on the female X chromosome may be a key factor. As women typically have half of their X chromosomes coated, whereas men have only one X chromosome, the coating may trigger stronger immune reactions in women.
The findings of this study enhance our understanding of the gender difference in diseases like lupus and could provide a theoretical basis for future targeted treatments and prevention. Researchers indicate that they will continue exploring how the molecular coating affects the immune system with the aim of providing more effective treatment options for patients.
【来源】http://www.chinanews.com/life/2024/02-05/10159140.shtml
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