红斑狼疮等自身免疫性疾病为何在女性中更为常见？科技日报记者张梦然从最新一期《细胞》杂志上带来了一项新的研究解释。研究发现，女性一半的X染色体上发现的分子涂层可能会引起不必要的免疫反应，这或许能为这一现象提供答案。
长期以来，科学家们一直困惑于为何女性比男性更容易患上红斑狼疮。新研究中，研究人员发现X染色体上的分子涂层在女性体内可能起到了关键作用。这一分子涂层的存在，可能导致免疫系统过度反应，从而引发红斑狼疮等疾病。
该研究为理解性别在红斑狼疮发病中的作用提供了新的视角，也为未来针对该疾病的治疗提供了新的研究方向。研究人员表示，通过进一步研究X染色体分子涂层的作用机制，有望为女性红斑狼疮患者带来更为有效的治疗手段。
Title: Why women are more susceptible to lupus than men
Keywords: lupus, women, X chromosome
News content:
A new study published in the latest issue of the journal “Cell” offers an explanation for why women are more prone to autoimmune diseases such as lupus. The findings suggest that a molecular coating on one half of the X chromosome in women may contribute to unnecessary immune reactions, potentially providing an answer to this long-standing puzzle.
Researchers have long been puzzled by the higher incidence of lupus in women compared to men. In the new study, they discovered that the molecular coating on the X chromosome may play a key role in females. The presence of this coating could lead to excessive immune responses, resulting in diseases such as lupus.
The findings offer a new perspective on the role of gender in the development of lupus and provide direction for future research and treatment. Researchers indicate that further study of the molecular coating’s mechanism on the X chromosome may lead to more effective treatments for female lupus patients.
【来源】http://www.chinanews.com/life/2024/02-05/10159140.shtml
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